Publications
Cell
Co-opting templated aggregation to degrade pathogenic tau assemblies and improve motor function
Miller L.V.C.*#, Papa G.*#, Vaysburd M., Cheng S, Sweeney P.W., Smith A., Katsinelos T., Huang M., Sanford S., Benn J., Farnsworth J., Higginson K., Joyner H, McEwan W.A.#, James L.C.# Cell (2024)
*co-first #co-corresponding author
EMBO Reports
IP6-stabilised HIV capsids evade cGAS/STING-mediated host immune sensing
Papa G., Albecka A., Mallery D.L., Vaysburd M., Renner N., James L.C. EMBO Reports (2023)
Cell Reports
CRISPR Csy4-mediated editing of Rotavirus double-stranded RNA genome
Papa G.*, Venditti L., Braga L., Giacca M., Petris G.*, Burrone O.R.* Cell Reports (2020) *co-corresponding author
Embo Journal
Liquid-liquid phase separation underpins the formation of replication factories in rotaviruses
Geiger F., Acker J., Papa G., Wang X., Arter W.E., Saar K.L., Erkamp N.A., Qi R., Bravo J.P., Strauss S., Krainer G., Burrone O.R., Jungmann R., Knowles T.P., Engelke H., Borodavka A. EMBO Journal (2021)
Nature
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion
Mlcochova, P., Kemp, S.A., Dhar, M.S., Papa G. … Gupta R.K. Nature (2019)
EMBO JOURNAL
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity
Caddy S.L., Vaysburd M., Papa G., Wing M., O’Connell K., Stoycheva D., Foss S., Andersen J.T., Oxenius A., James L.C. EMBO Journal (2020)
Other relevant publications
Vetter J., Papa G., Tobler K., Rodriguez J. M., Kley M., Myers M., Wiesendanger M., Schraner E. M., Luque D., Burrone O. R., Fraefel C., & Eichwald C. (2024). “The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication”. mBio, 15(4), e0049924.
Pauciullo S., Riccio A., Santopolo S., Albecka A., Papa G., James, L.C., Piacentini S., Lanzilli G., Rossi A., Santoro, M.G. (2024). “Human coronaviruses activate and hijack the host transcription factor HSF1 to enhance viral replication”. Cellular and Molecular Life Sciences, 81(1), 386.
Gaynor K. U., Vaysburd M., Harman M.A.J., Albecka A., Jeffrey P., Beswick P., Papa G., et al. (2023). “Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2”. Nature Communications, 14(1), 3583.
Strauss S., Acker J., Papa G., Desirò D., Schueder F., Borodavka A., & Jungmann R. (2023). “Principles of RNA recruitment to viral ribonucleoprotein condensates in a segmented dsRNA virus”. eLife, 12, e68670.
Vetter J.*, Papa G.*, Seyffert M., Gunasekera K., De Lorenzo G., Wiesendanger M., Reymond J. L., Fraefel C., Burrone O. R., & Eichwald C. (2022). “Rotavirus Spike Protein VP4 Mediates Viroplasm Assembly by Association to Actin Filaments”. Journal of Virology, e0107422. *Co-first author
Meng B., Abdullahi A., Ferreira IATM., Goonawardane N., Saito A., Kimura I., Yamasoba D., Gerber PP., Fatihi S., Rathore S., Zepeda SK., Papa G., et al. (2022) “Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity“. Nature. Feb 1. doi: 10.1038/s41586-022-04474.
Papa G.*, Burrone O.R. (2021). “Rotavirus reverse genetics: A tool for understanding virus biology”. Virus Research, 305, 198576. *corresponding author
Meng B.*, Kemp S.*, Papa G.* et al.(2021) “Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and role in B.1.1.7” Cell Reports, Jun 29;35(13):109292.; *Co-first author
Papa G., Mallery D.L., Albecka A., Welch L., Cattin-Ortolá J., Luptak J., Paul D., McMahon H.T., Goodfellow I.G., Carter A., Munro S., James L.C. (2021) “Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion” PLoS Pathogens 17(1): e1009246.
Papa G., Borodavka A., Desselberger U. (2021). “Viroplasms: Assembly and Functions of Rotavirus Replication Factories”. Viruses, 13(7), 1349.
Caddy S.*, Papa G.*, Borodavka A.*, Desselberger U. (2021). “Rotavirus research: 2014-2020”. Virus Research, 304, 198499. *contributed equally
Cattin-Ortola J., Welch L., Maslen S.L., Skehel M.J., Papa G., James L.C. and Munro S. (2021) “Sequences in the cytoplasmic tail of SARS-CoV-2 spike facilitate syncytia formation” Nature Communication, 2021 Sep 9;12(1):5333.
Eichwald C., De Lorenzo G., Schraner E.M., Papa G., et al. (2018) “Identification of a small molecule that compromises the structural integrity of viroplasms and rotavirus double-layered particles” Journal of Virology; 92(3):e01943-17.
Wiegand M.A., Gori-Savellini G., Gandolfo C., Papa G., Kaufmann C., Felder E., Ginori A., Disanto M.G., Spina D., Cusi M.G. (2017) “A Respiratory Syncytial Virus Vaccine Vectored by a Stable Chimeric and Replication-Deficient Sendai Virus Protects Mice without Inducing Enhanced Disease” Journal of Virology;91(10):e02298-16.
De Lorenzo G., Drikic M., Papa G., Eichwald C., Burrone OR, Arnoldi F. (2016) “An Inhibitory Motif on the 5’UTR of Several Rotavirus Genome Segments Affects Protein Expression and Reverse Genetics Strategies” PLoS One 11(11):e0166719.